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For in excess of 1 / 4 of a century, macrophage migration inhibitory component (MIF) continues to be a mysterious cytokine. in recent times, MIF has assumed a very important position like a pivotal regulator of innate immunity. MIF is definitely an integral ingredient of your host antimicrobial alarm process and anxiety response that encourages the pro-inflammatory capabilities of immune cells.
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As the main focus of this informative article is on innate immunity, we Restrict our dialogue on the possible therapeutic implications of MIF to sepsis and ARDS.
Cytokines are critical effector molecules of innate immunity that initiate and coordinate the cellular and humoral responses aimed, for example, at the eradication of microbial pathogens.
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